Small-scale laser based electron accelerators for biology and medicine: a comparative study of the biological effectiveness

Small-scale laser based electron accelerators for biology and medicine: a comparative study of the biological effectiveness
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L. Labate, M. G. Andreassi, F. Baffigi, G. Basta, R. Bizzarri, A. Borghini, G. Candiano, C. Casarino, M. Cresci, F. Di Martino, L. Fulgentini, F. Ghetti, M. C. Gilardi, A. Giulietti, P. Koester, F. Lenci, T. Levato, Y. Oishi, G. Russo, A. Sgarbossa, C. Traino, L. A. Gizzi

Proceedings of SPIE, vol. 8779 :  LASER ACCELERATION OF ELECTRONS, PROTONS, AND IONS II; AND MEDICAL APPLICATIONS OF LASER-GENERATED BEAMS OF PARTICLES II; AND HARNESSING RELATIVISTIC PLASMA WAVES III, Article Number: UNSP 87790O , (2013).

Abstract

Laser-driven electron accelerators based on the Laser Wakefield Acceleration process has entered a mature phase to be considered as alternative devices to conventional radiofrequency linear accelerators used in medical applications. Before entering the medical practice, however, deep studies of the radiobiological effects of such short bunches as the ones produced by laser-driven accelerators have to be performed. Here we report on the setup, characterization and first test of a small-scale laser accelerator for radiobiology experiments. A brief description of the experimental setup will be given at first, followed by an overview of the electron bunch characterization, in particular in terms of dose delivered to the samples. Finally, the first results from the irradiation of biological samples will be briefly discussed.

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